| | Day | Time | | Opponent | Score | | Record | |
| February |
| | 10 | 5:00 PM | @ | Northwest Florida State CC | L-1-5 | | Details |
| | | Game 2 | @ | Northwest Florida State CC | L-2-7 | | Details |
| | 12 | 3:00 PM | vs. | Lindenwood University | Canceled | 0-0 | Details |
| | Cancelled due to freezing weather & snow |
| | | 5:00 PM | vs. | Indiana Institute of Technology | Canceled | 0-0 | Details |
| | Cancelled due to freezing weather & snow |
| | 13 | 11:00 AM | vs. | McKendree University | Canceled | 0-0 | Details |
| | Cancelled due to freezing weather & snow |
| | | 1:00 PM | vs. | Union University (Tenn.) | Canceled | 0-0 | Details |
| | Cancelled due to freezing weather & snow |
| | | 3:00 PM | vs. | Indiana Institute of Technology | Canceled | 0-0 | Details |
| | Cancelled due to freezing weather & snow |
| | 18 | 1:00 PM | vs. | Northwest Florida State CC | W-5-2 | | Details |
| | | Game 2 | vs. | Northwest Florida State CC | L-2-5 | | Details |
| | 19 | 9:00 AM | vs. | Auburn-Montgomery | L-0-4 | 0-1 | Details |
| | AUM rated No. 22 in NAIA. Faulkner University Tournament, Montgomery, Ala. |
| | | 3:00 PM | vs. | Shorter University | L-4-9 | 0-2 | Details |
| | SC rated No. 18 in NAIA. Faulkner University Tournament, Montgomery, Ala. |
| | 20 | 3:00 PM | vs. | Reinhardt University | L-0-3 | 0-3 | Details |
| | Faulkner University Tournament, Montgomery, Ala. |
| | | 7:00 PM | @ | Faulkner University | L-1-4 | 0-4 | Details |
| | Faulkner University Tournament, Montgomery, Ala. |
| | 27 | 1:00 PM | @ | West Alabama | L-2-5 | 0-5 | Details |
| | UWA Invitational, Livingston, Ala. Live Stats |
| | | 3:00 PM | @ | West Alabama | L-0-3 | 0-6 | Details |
| | UWA Invitational, Livingston, Ala. Live Stats |
| | | 5:30 PM | vs. | Kentucky Wesleyan University | W-9-1 (6 Innings) | 1-6 | Details |
| | UWA Invitational, Livingston, Ala. Live Stats |
| March |
| | 3 | 1:00 PM | vs. | Notre Dame College | W-1-0 | 2-6 | Details |
| | Live Stats |
| | | Game 2 | vs. | Notre Dame College | W-7-6 | 3-6 | Details |
| | Live Stats |
| * | 5 | 1:00 PM | vs. | Dillard | W-19-0 (5 Innings) | 4-6 1-0 | Details |
| | Live Stats Brittany Abate pitches perfect game |
| * | | Game 2 | vs. | Dillard | W-18-1 (5 Innings) | 5-6 2-0 | Details |
| | Live Stats |
| | 7 | 11:00 AM | vs. | Lindsey Wilson | L-0-6 | 5-7 | Details |
| | University of Mobile Classic Live Stats |
| | 8 | 2:00 PM | vs. | Martin Methodist | L-0-8 (6 Innings) | 5-8 | Details |
| | Live Stats MMC rated No. 8 in NAIA |
| | | Game 2 | vs. | Martin Methodist | L-0-2 | 5-9 | Details |
| | 11 | 11:00 AM | vs. | Park University | Canceled | 5-9 | Details |
| | Game cancelled due to inclement weather |
| | 12 | 11:00 AM | vs. | Grand View University | L-0-1 | 5-10 | Details |
| | Gulf Coast Invitational, Orange Beach, Ala. |
| | | 3:00 PM | vs. | Oklahoma Christian University | L-0-1 | 5-11 | Details |
| | Gulf Coast Invitational, Orange Beach, Ala. |
| | 13 | 9:00 AM | vs. | Bethel University (Tenn.) | W-6-3 | 6-11 | Details |
| | Gulf Coast Invitational, Orange Beach, Ala. |
| | | 2:30 PM | vs. | McKendree University | L-4-6 | 6-12 | Details |
| | Gulf Coast Invitational, Orange Beach, Ala. |
| | 14 | 9:00 AM | vs. | Campbellsville University | L-0-12 (5 Innings) | 6-13 | Details |
| | Gulf Coast Invitational, Orange Beach, Ala. |
| | 16 | 12:00 PM | vs. | Birmingham-Southern | W-4-3 | 7-13 | Details |
| | BSC - NCAA Div. III Live Stats |
| | | Game 2 | vs. | Birmingham-Southern | W-5-1 | 8-13 | Details |
| | BSC - NCAA Div. III Live Stats |
| | 19 | 4:00 PM | @ | Thomas University (Ga.) | W-4-2 | 9-13 | Details |
| | Thomas University Tournament, Thomasville, Ga. |
| | | 6:00 PM | vs. | LSU-Alexandria | W-7-5 | 10-13 | Details |
| | Thomas University Tournament, Thomasville, Ga. (Zeringue walk-off 2-run homer in bottom of 7th) |
| | 20 | 10:00 AM | vs. | LSU-Alexandria | W-5-2 | 11-13 | Details |
| | Thomas University Tournament, Thomasville, Ga. |
| | | 2:00 PM | @ | Thomas University (Ga.) | W-2-1 | 12-13 | Details |
| | Thomas University Tournament, Thomasville, Ga. |
| * | 24 | 3:00 PM | @ | William Carey | L-0-3 | 12-14 2-1 | Details |
| | Live Stats |
| * | | Game 2 | @ | William Carey | L-1-7 | 12-15 2-2 | Details |
| | Live Stats |
| * | 26 | 4:00 PM | @ | University of Mobile | L-1-2 (8 Innings) | 12-16 2-3 | Details |
| | Mobile rated No. 25 in NAIA |
| * | | Game 2 | @ | University of Mobile | L-0-2 | 12-17 2-4 | Details |
| | Mobile rated No. 25 in NAIA |
| | 27 | 2:00 PM | vs. | Lindenwood University | W-5-3 | 13-17 | Details |
| | | Game 2 | vs. | Lindenwood University | W-2-1 (8 Innings) | 14-17 | Details |
| | 29 | 12:00 PM | vs. | Columbia College (MO) | L-3-4 | 14-18 | Details |
| | Live Stats |
| | | Game 2 | vs. | Columbia College (MO) | W-6-3 | 15-18 | Details |
| | Live Stats |
| April |
| * | 1 | 12:00 PM | vs. | William Carey | L-1-4 | 15-19 2-5 | Details |
| | WCU rated No. 14 in NAIA Live Stats |
| * | | Game 2 | vs. | William Carey | L-1-8 | 15-20 2-6 | Details |
| | WCU rated No. 14 in NAIA Live Stats |
| | 10 | 12:00 PM | vs. | Thomas University (Ga.) | W-9-0 (5 Innings) | 16-20 | Details |
| | | Game 2 | vs. | Thomas University (Ga.) | L-6-7 (9 Innings) | 16-21 | Details |
| * | 12 | 1:00 PM | vs. | Belhaven University | L-0-1 (8 Innings) | 16-22 2-7 | Details |
| | Live Stats |
| * | | Game 2 | vs. | Belhaven University | W-1-0 | 17-22 3-7 | Details |
| | Live Stats |
| | 14 | 5:00 PM | @ | Birmingham-Southern | L-0-8 (6 Innings) | 17-23 | Details |
| | BSC - NCAA Div. III Live Stats |
| | | Game 2 | @ | Birmingham-Southern | W-5-0 | 18-23 | Details |
| | BSC - NCAA Div. III Live Stats |
| * | 18 | 12:00 PM | vs. | University of Mobile | L-1-2 (8 Innings) | 18-24 3-8 | Details |
| | Senior Day Live Stats |
| * | | Game 2 | vs. | University of Mobile | L-2-3 | 18-25 3-9 | Details |
| | Senior Day Live Stats |
| * | 20 | 1:00 PM | @ | Dillard | W-20-0 (5 Innings) | 19-25 4-9 | Details |
| | Coach Sellers-Cook's 100th Win |
| * | | Game 2 | @ | Dillard | W-20-0 (5 Innings) | 20-25 5-9 | Details |
| * | 22 | 3:00 PM | @ | Belhaven University | L-4-6 | 20-26 5-10 | Details |
| | BU rated No. 6 in NAIA Live Stats |
| * | | Game 2 | @ | Belhaven University | L-1-2 | 20-27 5-11 | Details |
| | BU rated No. 6 in NAIA Live Stats |
| | 29 | 3:00 PM | vs. | Dillard | W-16-1 (5 Innings) | 21-27 | Details |
| | GCAC Tournament @ Gulf Shores, Ala. - Apr. 29-30, 2010 Live Stats |
| | | 5:30 PM | vs. | Belhaven University | L-0-4 | 21-28 | Details |
| | GCAC Tournament @ Gulf Shores, Ala. - Apr. 29-30, 2010 Live Stats |
| | 30 | 10:00 AM | vs. | University of Mobile | L-1-6 | 21-29 | Details |
| | GCAC Tournament @ Gulf Shores, Ala. - Apr. 29-30, 2010 |